Zum Inhalt springen

59. Journal Club 14.6.2023

Themen:

  1. Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture
  2. Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment
  3. Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials
  4. Albuminuria-lowering effect of dapagliflozin, exenatide, and their combination in patients with type 2 diabetes: A randomized cross-over clinical study
  5. The Colorectal cancer RISk Prediction (CRISP) trial: a randomised controlled trial of a decision support tool for risk-stratified colorectal cancer screening
Background: Clinical guidelines recommend low-molecular-weight heparin for thromboprophylaxis in patients with fractures, but trials of its effectiveness as compared with aspirin are lacking. Methods: In this pragmatic, multicenter, randomized, noninferiority trial, we enrolled patients 18 years of age or older ...
Abstract Importance  The association between statin-induced reduction in low-density lipoprotein cholesterol (LDL-C) levels and the absolute risk reduction of individual, rather than composite, outcomes, such as all-cause mortality, myocardial infarction, or stroke, is unclear. Objective  To assess the association between ...
Abstract Objective: To study the efficacy and safety of lasmiditan for acute treatment of migraine in patients using migraine preventive medications. Background: While lasmiditan has been proven to be an effective acute treatment for migraine, its effectiveness has not been ...
Annemarie B. van der Aart-van der Beek PharmD, Ellen Apperloo MD, Niels Jongs PhD, Dennis B. Rouw MD, C. David Sjöström MD, Iris Friedli PhD, Lars Johansson PhD, Daniël H. van Raalte MD, Klaas Hoogenberg MD, Hiddo J. L. Heerspink PhD ZielBewertung der Albuminurie-senkenden Wirkung von Dapagliflozin, Exenatid und ...
BACKGROUND: A risk-stratified approach to colorectal cancer (CRC) screening could result in a more acceptable balance of benefits and harms, and be more cost-effective. AIM: To determine the effect of a consultation in general practice using a computerised risk assessment ...