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62. Journal Club 25.10.2023

Themen:

  1. Risk of adverse events following the initiation of antihypertensives in older people with complex health needs: a self-controlled case series in the United Kingdom
  2. Bessere Behandlung durch „Peer effect“ – Qualitätszirkel, App Gruppen oder ListServer
  3. Association Between Consumption of Ultraprocessed Foods and Cognitive Decline
  4. Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes (NOAH)
  5. Edoxaban versus Warfarin in Patients with Atrial Fibrillation
Background We assessed the risk of adverse events—severe acute kidney injury (AKI), falls and fractures associated with use of antihypertensives in older patients with complex health needs (CHN).SettingUK primary care linked to inpatient and mortality records.MethodsThe source population comprised patients ...
Experimental evidence for structured information–sharing networks reducing medical errors Damon Centola et al; https://ndg.asc.upenn.edu/wp-content/uploads/2023/07/pnas.2108290120.pdf Der Austausch unter Kollegen kann die Gefahr von ärztlichen Diagnose- und Behandlungsfehlern vermindern. Dies zeigen die Ergebnisse einer experimentellen Studie in der Ärzte ihre diagnostischen und ...
Question: Is the consumption of ultraprocessed foods associated with cognitive decline?Findings: In a cohort study of 10 775 individuals, higher consumption of ultraprocessed foods was associated with a higher rate of global and executive function decline after a median follow-up of ...
NOAH-AFNET 6 Studie - TERMINATED following a recommendation from the data safety and monitoring board due to safety concerns and a tendency towards futility. Study OverviewBrief SummaryNOAH is an investigator-initiated, prospective, parallel-group, double-blind, randomised, multi-centre trial. The objective of the ...
ENGAGE-TIMI 48 trial BACKGROUNDEdoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODSWe conducted a randomized, double-blind, double-dummy ...